Advanced Pediatrics

Women who used the drug during pregnancy gave birth to babies with birth defects, including cleft palates and lips, club feet, heart defects and craniosynostosis – a condition in which the skull is abnormally shaped and may not have enough space for the brain. This can cause vision problems, eating issues and mental impairment.

The study of 900,000 Danish women in August 2013 review found “2-fold increased risk of cardiac malformations with ondansetron (Zofran), leading to an overall 30 percent increased risk of major congenital malformations.”

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